Halotestin side effects should start with a single oral medication on the first day of menstrual bleeding. Thereafter, for 20 days is necessary to take one tablet daily. This is followed by a seven-day break from taking the drug. Usually, a few days after taking the pills comes menstrual-like bleeding.
The next cycle should begin receiving Silest on the eighth day, ie seven days after discontinuation of the tablets in the previous cycle. The first cycle of the new tablet should be taken regardless of whether stopped or is still ongoing bleeding. In a blister pack affixed preparation days of the week. For the convenience of checking the regularity of taking the pills is recommended to start a new cycle with a pill marked with the data of day of the week, and continue to continue without interruption the entire cycle of administration.
Contraceptive pills have the highest efficiency, if taken at one and the same time of day, for example, in the morning.
In case of skipping the usual time of receipt, the tablet should be taken immediately. Retreat from the ordinary reception time up to 12 hours provides a reliable contraceptive effect. Efficacy is reduced by the delay in taking the pill more than 12 hours. If the usual time of the drug more than 12 hours or missed reception of more than one tablet, the drug should be resumed immediately, leaving the package missed tablet. However, before the end of this cycle should use additional means of protection against pregnancy, such as condoms or vaginal contraceptive suppository. In such situations, you can not rely on the method of “safe days” or “temperature” method of contraception.
After the birth of halotestin side effects a child receiving Silest should be started no earlier than 4 weeks after delivery, provided that the woman is not breastfeeding.
After an abortion or miscarriage on term up to 20 weeks of pregnancy pill intake, you can start immediately, in these cases the use of additional contraception is needed. After an induced or spontaneous abortion on gestational age over 20 weeks of hormonal contraceptives can be used to start at day 21 post-abortion or on the first day of menstruation natural appearance (whichever comes first). In these cases, during the first 7 days of the cycle is recommended to use additional local contraceptives in addition to receiving Silest. In exceptional cases, if there is medical evidence to ensure immediate reliable contraception, Silest reception can be initiated 1 week after abortion. It should be borne in mind that the risk of thromboembolic complications increased with the admission to the post-abortion.
If you have vomiting or diarrhea Silest can lose its effectiveness, as it takes 4 hours for a full assimilation by the body of the tablet. In this case, it is recommended to continue receiving Silest, complementing its action other contraceptives before the onset of menstruation.
Side effects Cardiovascular system : hypertension, myocardial infarction, cerebrovascular accident, deep vein thrombosis, arterial thrombosis, pulmonary or other vessels, swelling. Tumors : benign and malignant liver tumors, cervical cancer and breast cancer. Hepatobiliary system : cholestatic jaundice, BaddaKiari syndrome, intrahepatic cholestasis, cholelithiasis. Gastrointestinal tract : nausea, vomiting, abdominal pain, flatulence, colitis. Genitals : intermenstrual bleeding, spotting, amenorrhea, changes in the menstrual cycle, increase in fibroid size of the uterus, vaginal candidiasis increase in cervical secretions, cervical erosion, decreased libido, PMS, temporary infertility after discontinuation of the drug breast cancer : pain and sense of tension, galactorrhea, engorgement, increase in size, a reduction of lactation at the reception immediately after birth. Skin : erythema nodosum, skin rash, chloasma, erythema, acne, seborrhea, alopecia, hirsutism, pigmentation spots on the face, hypertrichosis, pemphigoid (gestational herpes), melasma with a tendency to persistence. organ of vision : cataracts, lesions of the optic nerve, changes in corneal curvature, discomfort while wearing contact lenses. Central nervous system : headache, mood changes, irritability, depression, chorea. Metabolism : fluid retention, weight change (increase or decrease), reduced glucose tolerance, change in appetite. kidney : reduction of renal function, hemolytic -uremichesky syndrome. Other :. dizziness, migraine When menstrual-like bleeding, reception Silest should continue. If the bleeding does not stop, it is necessary to conduct a survey to exclude organic causes. These recommendations concern and spotting that can occur sporadically for several cycles or receiving Silest first time after a prolonged ingestion. If at the end of the cycle of the drug the bleeding does not occur, it is necessary to exclude pregnancy before starting a new cycle of receiving Silest.
No serious cases halotestin side effects of poisoning due to overdose Silest not mentioned. In case of overdose can cause nausea, vomiting, and vaginal bleeding.
No specific antidote exists. In case of overdose should be gastric lavage (within the first hour after ingestion) and symptomatic therapy.
Interaction with other medicinal products and other forms of interaction
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Drugs that cause the induction of enzymes that metabolize estrogens (eg, estrogen 2-hydroxylase – coenzyme 3A4 cytochrome P-450), reduce the contraceptive efficacy of hormonal drugs. It is also possible that the induction of these same isozymes may result in a reduction in blood concentration of the drug Silest progestogen component. Potentially clinically significant in this respect are the drugs and herbal drugs affecting enzymes which are involved in the biotransformation of contraceptive steroid (for example, St. John’s wort, barbiturates, carbamazepine, phenytoin, sulfonamides, pyrazolone derivatives, rifampicin).
It has been shown that some inhibitors protease and some antiretroviral drugs increase (for example, indinavir) or lower (e.g., ritonavir) halotestin side effects concentration in the blood combined hormonal contraceptives.
Another type of interaction is to tackle intrahepatic circulation estrogens, whereby elimination is accelerated and reduces the concentration of ethinyl estradiol. When co-administered with some antibiotics (such as ampicillin or tetracycline) was observed lack of estrogen conjugates cleavage of fatty acids by intestinal bacteria. how much to inject for weight loss
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