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Halotestin 10

fluoxymesterone halotestin

It is not known whether this drug in human milk. Because many drugs are determined in human milk, should stop breast-feeding or stop taking the drug, taking into account the importance of the treatment to the mother.

special instructions

In connection fluoxymesterone halotestin with the suppression of bone marrow function, it should be analyzed weekly blood cells for at least six weeks after taking the prescribed dose.

Along with the study of pulmonary function in patients before starting treatment, repeated studies during treatment should be carried out. For high-risk group includes patients with the proper performance of forced vital capacity and lung diffusion capacity below 70%.

Since Shiina may impair liver function, you must periodically carry out appropriate analyzes. You should also periodically check kidney function.

Side effect

Digestive tract

After 3-6 hours after administration Shiina may experience nausea and vomiting that typically last up to 24 hours. The frequency and duration of these side effects can be reduced through the use of antiemetic drugs before taking Shiina, as well as through the appointment Shiina patients fasting.

Toxicity with respect to the hematopoietic system

The main fluoxymesterone halotestin and the most severe toxicity associated with late Shiina suppression of bone marrow function, which usually occurs within 4-6 weeks after drug administration and is dose-dependent.Thrombocytopenia develops an average of 4 weeks and may persist for 1-2 weeks. Approximately 6 weeks after receiving Shiina develop leukopenia, persistent for 1-2 weeks. Approximately 65% of patients with WBC counts may be less than 5000 / mm 3 and 36% of patients less than 3000 / mm 3 . Typically, thrombocytopenia is more severe than leukopenia. However, both types of toxicity may limit the dose.

Shiina may cause cumulative myelosuppression, and after receiving repeated doses may experience more pronounced bone marrow suppression or myelosuppression duration can be greater. It was reported on acute leukemia and bone marrow dysplasias as a result of treatment nitrosourea drugs.

There may also be anemia, but it develops less often and is less severe, than thrombocytopenia and leukopenia.

The toxic effects on the lungs

In rare cases it reported appearance of infiltrates in the lungs and / or lung fibrosis Shiina during use. The appearance of toxic effects observed after 6 months (or over longer periods) after the start of treatment with cumulative doses of the drug more than 1100 mg / m 2 . It reported one case of pulmonary toxicity at a cumulative dose of only 600 mg.

Other toxic effects

In rare cases, it noted the appearance of stomatitis, alopecia and anemia. A number of patients treated with Shiina, observed neurological reactions such as confusion, lethargy, ataxia, and speech articulation disorder. However, the relationship of these effects to the drug intake in these patients has not been established.


In patients receiving high cumulative doses of the drug in a long-term treatment Shiina and other drugs nitrosoureas, marked renal dysfunction, is a reduction of kidney size, progressive azotemia and renal failure. Occasionally also reported kidney damage in patients receiving lower total doses.

Toxic effects on the liver

It was reported a reversible toxic effect on the liver, manifested in the fluoxymesterone halotestin increase in transaminases, alkaline phosphatase and bilirubin, a small percentage of patients treated with Shiina.


Dosing and Administration

Shiina recommended dose in adults and children is 130 mg / m 2 after a single ingestion every 6 weeks.

In patients with reduced bone marrow function the dose can be reduced  , while maintaining a six-week interval between doses.

Repeated courses Shiina should not be used when the number of platelets less and the number of white blood cells less than 4000 / mm 3 , because the hematologic toxicity is late and is cumulative. The content of blood cells should be checked weekly.


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fluoxymesterone halotestin

The drug is administered intravenously slowly for at least 60 minutes, at 250-500 mg 1-2 times a day. Doses are determined by the nature and severity of the infection and the sensitivity of the alleged pathogen.

From the digestive fluoxymesterone halotestin system: nausea, vomiting, diarrhea (including blood), indigestion, loss of appetite, abdominal pain, colitis psevdomsmbranozny; increased activity of “liver” transaminases, hyperbilirubinemia, hepatitis, dysbiosis.

Cardio-vascular system: decrease in blood pressure, circulatory collapse, tachycardia, atrial fibrillation, prolongation of the interval .

From a metabolism: hypoglycaemia (increased appetite, increased sweating, trembling).

From the nervous system: headache, dizziness, weakness, sleepiness, insomnia, tremor, anxiety, paresthesia, anxiety, hallucinations, confusion, depression, movement disorders, convulsions, seizures (in predisposed patients).

From the senses: blurred vision, hearing, smell, taste and tactile sensitivity.

From the musculoskeletal system: arthralgia, muscle weakness, myalgia, tendon rupture, tendivit, rhabdomyolysis.

From the urinary system: giperkreatinemiya, interstitial nephritis, acute renal failure.

From the side of hematopoiesis: eosinophilia, hemolytic anemia, leukopenia, neutropenia, agranulocytosis, thrombocytopenia, pancytopenia, hemorrhage.

Allergic reactions: itching, and flushing of the skin, swelling of the skin and mucous membranes, urticaria, malignant exudative erythema (Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell’s syndrome), bronchospasm, asthma, anaphylactic shock, hypersensitivity pneumonitis, vasculitis.

Local reactions: pain, redness at the injection site, phlebitis.

Other: fatigue, aggravation fluoxymesterone halotestin of porphyria, persistent fever, the development of superinfection, photosensitization.

Overdosing Symptoms : nausea, erosive lesions of the mucous membranes of the gastrointestinal tract, the lengthening of the interval QT, confusion, dizziness, seizures. Treatment : symptomatic, dialysis is ineffective.

Interaction with other drugs
increases the half-life of cyclosporin.

Nonsteroidal anti-inflammatory drugs, theophylline, increase the risk of seizures, corticosteroids increase the risk of tendon rupture.

Cimetidine and drugs that block tubular secretion, slows down.

Levofloxacin compatible infusion solution with 0.9% sodium chloride, 5% dextrose, Ringer’s solution, 2.5% dextrose, combined solutions for parenteral nutrition (amino acids, carbohydrates, electrolytes).

You can not mix with heparin and solutions having an alkaline reaction.

Specific guidance
After normalization of body temperature, it is recommended to continue treatment for at least 48-72 hours.

The duration of an intravenous infusion of 500 mg (100 ml infusion solution) should be at least 60 minutes.

During treatment should avoid sunlight and artificial UV radiation in order to avoid damage to the skin (photosensitivity).

If signs of tendinitis, pseudomembranous colitis levofloxacin immediately overturned.

It should be borne in mind that in patients with brain damage history (stroke, major trauma) may develop seizures, with insufficient glucose-6-phosphate dehydrogenase – the risk of hemolysis.

In the period of treatment must be careful when driving vehicles and occupation of other potentially hazardous activities that require high concentration and psychomotor speed reactions.

In the course of therapy should be aware of the possibility of superinfection development.

With the combination fluoxymesterone halotestin of levofloxacin with vitamin K antagonists should be monitored for indicators of blood coagulation. Running low dose t3 clen cycle trying to lose bodyfat isn’t a real hot idea imo. bodybuilding frauen klassen Anabolika kaufen l arginin bodybuilding